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phenobarbital will lower the level or influence of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Powerful or moderate CYP3A4 inducers might raise charge of diazepam elimination; therefore, efficacy of diazepam may very well be lowered.Habit Forming. Phenobarbital could possibly be habit forming. Tole